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Do Large Clinical Trials Adequately Consider Individual Patient Physiology? Debating The RELIEF Study

By Michael Keane, BMBS, FANZCA and Shashikanth Manikappa, MD, DNB, FANZCA
February 21, 2019

Patient safety requires a well-informed debate about the rationale of large, randomized controlled trials (RCTs) and whether, by their very nature, they can adequately consider the unique physiology of every individual patient. 

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WAKE-UP Time for Thrombolysis in Acute Stroke?

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By Martina McGrath, MD
October 30, 2018

MRI thrombolysis for stroke of unknown time of onset

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Prior studies have suggested a particular pattern may be seen on an MRI of the brain in the early hours following stroke onset; a visible ischemic lesion on diffusion-weighted imaging along with the lack of a hyperintense signal in the same area on fluid-attenuated inversion recovery (FLAIR). The benefit of aggressive stroke intervention in patients with the combination of unknown time of symptom onset and this particular signal mismatch on MRI brain scans is unknown. Continue reading “WAKE-UP Time for Thrombolysis in Acute Stroke?”

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By Olivier Lucar
October 16, 2018

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By Connor Emdin
September 26, 2018

Eureka EasyClean Deluxe Lightweight Handheld Vacuum Cleaner Hand Vac Corded 72AEureka Mighty Mite Bagged Canister Vacuum Cleaner Pet, 3684F-purpleEureka NEU182A PowerSpeed Lightweight Bagless Upright Vacuum Cleaner, blueeeeEureka Style F&G Upright Vacuum Cleaner Bags 80 Pk Made in USA Continue reading “Use of Guideline-Recommended Medical Therapy in Patients with Heart Failure”

Restrictive versus Liberal Fluid Therapy in Abdominal Surgery

By Connor Emdin
August 28, 2018

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Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?

By Martina McGrath, MD
August 8, 2018

It is estimated that 1 in every 7.5 people in the US will die of sudden cardiac death.DeWALT DWST08203 ToughSystem Case Tool Equipment Box - Large Survival following out-of-hospital cardiac arrest has increased in recent years, from 10.2% in 2006, to 12.4% in 2015.1 However, only 9% of those surviving to hospital discharge were classified as having good functional status. Therefore, significant long-term neurologic impairment is a common outcome of cardiac arrest. Continue reading “Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?”

Cervical Cancer Screening Using HPV Testing Alone: Are We There Yet?


By Martina McGrath, MD
July 18, 2018

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CLC 5625XL Padded Comfort Belt, 5-Inch Wide, Extra Large Tool Belts nbsull26-Tool Bags, Belts & Pouches

Item specifics

New with tags: A brand-new, unused, and unworn item (including handmade items) in the original packaging (such as ... Read moreabout the condition

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Model Number: 5625XL



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Category: Tool Belts Size: waist sizes 47 inches to 56 inches

Dulaglutide in Type 2 Diabetes: Do GLP-1 agonists delay progression of diabetic nephropathy?

Dibea D008 Pro Wireless 2-in-1 Vacuum Cleaner Handheld Powerful Cleaner 9Kpa New

By Connor Emdin
June 27, 2018

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Procalcitonin-Guided Antibiotic Therapy in Lower Respiratory Tract Infection: Is It Safe?

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By Martina McGrath, MD
June 5, 2018

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General International Dust Collector With Metal Drum 1.5 HP Portable 13 Gal

By Lea Borgi, MD
May 16, 2018

Genuine CONNECT 36996 16 Storage Bin System c w Magnetic Bar For Tool StorageGenuine Joe 45 Gallon Brown Garbage Bags, 40x46, 0.6mil, 250 Bags (GJO02151)Genuine Kenmore Model 116.2641381, Unit Motor, part, power, electric, main, OEM Continue reading “Does Menu Labeling Lead to Healthier Food Choices?”