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Do Large Clinical Trials Adequately Consider Individual Patient Physiology? Debating The RELIEF Study

By Michael Keane, BMBS, FANZCA and Shashikanth Manikappa, MD, DNB, FANZCA
February 21, 2019

Patient safety requires a well-informed debate about the rationale of large, randomized controlled trials (RCTs) and whether, by their very nature, they can adequately consider the unique physiology of every individual patient. 

Panasonic wrist blood pressure monitor light pink EW-BW13-M JapanPanaVise 381 Vacuum Base PanaVisePanel Clip Retainer to suit Honda Pk 50 Part No. 36366 By Connect - New  Continue reading “Do Large Clinical Trials Adequately Consider Individual Patient Physiology? Debating The RELIEF Study”

WAKE-UP Time for Thrombolysis in Acute Stroke?

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By Martina McGrath, MD
October 30, 2018

MRI thrombolysis for stroke of unknown time of onset

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Prior studies have suggested a particular pattern may be seen on an MRI of the brain in the early hours following stroke onset; a visible ischemic lesion on diffusion-weighted imaging along with the lack of a hyperintense signal in the same area on fluid-attenuated inversion recovery (FLAIR). The benefit of aggressive stroke intervention in patients with the combination of unknown time of symptom onset and this particular signal mismatch on MRI brain scans is unknown. Continue reading “WAKE-UP Time for Thrombolysis in Acute Stroke?”

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By Olivier Lucar
October 16, 2018

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Single High End JBL LX300 Stereo Bookshelf Speaker

By Connor Emdin
September 26, 2018

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Restrictive versus Liberal Fluid Therapy in Abdominal Surgery

By Connor Emdin
August 28, 2018

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Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?

By Martina McGrath, MD
August 8, 2018

It is estimated that 1 in every 7.5 people in the US will die of sudden cardiac death.SK Facom 10 pc Fast Action Combination Wrench Set Metric 40R.JE10 Survival following out-of-hospital cardiac arrest has increased in recent years, from 10.2% in 2006, to 12.4% in 2015.1 However, only 9% of those surviving to hospital discharge were classified as having good functional status. Therefore, significant long-term neurologic impairment is a common outcome of cardiac arrest. Continue reading “Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?”

Cervical Cancer Screening Using HPV Testing Alone: Are We There Yet?

SK Hand Tools 40964 1 4-inch Drive SuperKrome Extension 14-inch

By Martina McGrath, MD
July 18, 2018

PEX-1632 Manual Clamping Clamp Tools Pipe Manual Tool Maintenance-Free 16-32mmPFEIL Swiss Made 8mm No. 5 GougePFERD 12079 6-1 4 Round Needle File Knurled Handle, Cut 4 (12 pk)Phase Technology 5 1 4 RPF Midrange Solid Piston Drivers - M434 - Great SK Professional 10 L Crimper w Die, 22 to 10 AWG - 15011

Sealey VSE2515 TDC Tool M14 x 1.25mm - Alfa Romeo, Fiat Position nbtkpq7057-Other Hand Tools

Item specifics

Condition:
New: A brand-new, unused, unopened, undamaged item in its original packaging (where packaging is ... Read moreabout the condition
Manufacturer: Sealey
Brand:

Sealey

Length: 20
Height: 290 Diameter: 20
Manufacturer Part Number:

VSE2515

MPN:

VSE2515

EAN:

5051747684218

UPC:

Does Not Apply

ISBN:

Does Not Apply

Dulaglutide in Type 2 Diabetes: Do GLP-1 agonists delay progression of diabetic nephropathy?

SK PROFESSIONAL TOOLS 86223 Combo Wrench Set,Chrome,6-22mm,16 Pc

By Connor Emdin
June 27, 2018

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Procalcitonin-Guided Antibiotic Therapy in Lower Respiratory Tract Infection: Is It Safe?

SK PROFESSIONAL TOOLS SKT9006 Torque Wrench Head,Open End,5 8 In.

By Martina McGrath, MD
June 5, 2018

Piede di Porco Set - 400mm 2pc Parte N.7042 da Laser -Pince profil V pour Viper P Virax SK PROFESSIONAL TOOLS Steel Hand Ratchet,1 2 Dr.,15 L, 40170

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Pinnacle Speakers PK ID PC12A Subwoofer ONLY

By Lea Borgi, MD
May 16, 2018

PINZE PIEGATRICI PER LAMIERE 436G SCUPioneer S-FCRW2500 Speaker System 5 Speaker and 1 Subwoofer SetPioneer SW-E10 600 Watt Powered Elite Subwoofer Continue reading “Does Menu Labeling Lead to Healthier Food Choices?”